Characteristics of chromosome instability in the human lymphoblast cell line WTK1.

@article{Schwartz2001CharacteristicsOC,
  title={Characteristics of chromosome instability in the human lymphoblast cell line WTK1.},
  author={Jeffrey L. Schwartz and Robert Jordan and Helen H. Evans},
  journal={Cancer genetics and cytogenetics},
  year={2001},
  volume={129 2},
  pages={124-30}
}
The characteristics of spontaneous and radiation-induced chromosome instability were determined in each of 50 individual clones isolated from control populations of human lymphoblasts (WTK1), as well as from populations of these cells previously exposed to two different types of ionizing radiation, Fe-56 and Cs-137. The types of chromosome instability did not appear to change in clones surviving radiation exposure. Aneuploidy, polyploidy, chromosome dicentrics and translocations, and chromatid… CONTINUE READING