Characteristics of catechin- and theaflavin-mediated cardioprotection.

  title={Characteristics of catechin- and theaflavin-mediated cardioprotection.},
  author={Henryk Dreger and Mario Lorenz and Alexandra Kehrer and Gert Baumann and Karl Stangl and Verena Stangl},
  journal={Experimental biology and medicine},
  volume={233 4},
Catechins and theaflavins-the main polyphenolic substances of green and black tea, respectively-exert a plethora of beneficial effects on the cardiovascular system. In a model of H(2)O(2)-mediated oxidative stress, we investigated the effects of epigallocatechin-3-gallate (EGCG) and theaflavin-3,3'-digallate (TF3) on neonatal rat cardiomyocytes. Pretreatment with EGCG or TF3 1 hr prior to induction of oxidative stress by H(2)O(2) effectively protected cardiac myocytes as determined by measuring… CONTINUE READING


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