Characteristics of canine melanomas and comparison of histology and DNA ploidy to their biologic behavior.

@article{Bolon1990CharacteristicsOC,
  title={Characteristics of canine melanomas and comparison of histology and DNA ploidy to their biologic behavior.},
  author={Brad N. Bolon and M B Calderwood Mays and Benjamin J Hall},
  journal={Veterinary pathology},
  year={1990},
  volume={27 2},
  pages={96-102}
}
The biologic behavior of 179 formalin-fixed, paraffin-embedded canine melanomas was correlated with their histologic appearance. In addition, flow cytometric analysis of DNA content was performed on 54 of these tumors. Histologic examination accurately predicted clinical course in 89% of the melanomas with known behavior. Flow cytometry accurately predicted behavior in 93% of tumors with diagnostic histograms and demonstrated malignant features in 100% of metastases from malignant oral tumors… CONTINUE READING