Characteristics of and calcium requirements for histamine release from rat peritoneal mast cells treated with concanavalin A.

Abstract

Concanavalin A (Con A) produced a selective release of histamine from rat peritoneal mast cells in the presence and absence of added calcium. Secretion under both conditions was enhanced by adenosine, but only the former release was potentiated by phosphatidyl serine (PS). The latter release was abolished by depletion of intracellular reservoirs of calcium… (More)

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