Characteristics of an Albumin Cobalt Binding Test for assessment of acute coronary syndrome patients: a multicenter study.

  title={Characteristics of an Albumin Cobalt Binding Test for assessment of acute coronary syndrome patients: a multicenter study.},
  author={Robert H M Christenson and Show Hong Duh and Wendy R. Sanhai and Alan H. B. Wu and V Holtman and P. Painter and E Branham and Fred S. Apple and Masami Murakami and Deborah L. Morris},
  journal={Clinical chemistry},
  volume={47 3},
BACKGROUND The ability of the N-terminal region of human albumin to bind cobalt is diminished by myocardial ischemia. The characteristics of an assay based on albumin cobalt binding were assessed in suspected acute coronary syndrome patients and in a control reference population. The ability of the Albumin Cobalt Binding (ACB) Test measurement at presentation to predict troponin-positive or -negative results 6-24 h later was also examined. METHODS We enrolled 256 acute coronary syndrome… CONTINUE READING


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