Characteristics of age-related changes in cultured human vocal fold fibroblasts.

@article{Chen2008CharacteristicsOA,
  title={Characteristics of age-related changes in cultured human vocal fold fibroblasts.},
  author={Xia Chen and Susan L Thibeault},
  journal={The Laryngoscope},
  year={2008},
  volume={118 9},
  pages={
          1700-4
        }
}
OBJECTIVES/HYPOTHESIS Normal human vocal fold fibroblast (hVFF) primary cell lines are unavailable commercially and are very difficult to acquire, subsequently little is known about their characteristics. The purpose of this study was to compare the morphological and proliferation characteristics and gene expression of hVFFs from different aged donors. STUDY DESIGN In vitro. METHODS We developed three normal hVFF primary cell lines from donors aged 21 (21T), 59 (59T) and 79 (79T) years. We… CONTINUE READING
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