Characteristics of age-related behavioral changes in senescence-accelerated mouse SAMP8 and SAMP10.

@article{Miyamoto1997CharacteristicsOA,
  title={Characteristics of age-related behavioral changes in senescence-accelerated mouse SAMP8 and SAMP10.},
  author={Masaomi Miyamoto},
  journal={Experimental gerontology},
  year={1997},
  volume={32 1-2},
  pages={139-48}
}
Senescence-Accelerated Mouse (SAM), a murine model of accelerated senescence, has been established by Takeda et al. (1981). SAM consists of senescence-accelerated-prone mouse (SAMP) and senescence-accelerated-resistant mouse (SAMR), the latter of which shows normal aging characteristics. In 1991 there were eight different substrains in the P-series, which commonly exhibited accelerated aging with a shortened life span (Takeda et al., 1991). Among the P-series, we have found that SAMP8 mice show… CONTINUE READING
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