Characteristics of Long‐term Alprazolam Users in the Community

@article{Romach1992CharacteristicsOL,
  title={Characteristics of Long‐term Alprazolam Users in the Community},
  author={M. Romach and G. Somer and L. Sobell and M. Sobell and H. Kaplan and E. Sellers},
  journal={Journal of Clinical Psychopharmacology},
  year={1992},
  volume={12},
  pages={316–321}
}
The widespread use of benzodiazepines remains a source of concern to the medical profession and the general public, especially as newer compounds come on the market. Our goal was to characterize long-term alprazolam users in the community and to determine whether such use represented abuse or behavioural dependence. We conducted three community surveys to learn about the natural history of long-term alprazolam use. Current long-term alprazolam users (those using the drug for 3 months or longer… Expand
Clinical aspects of chronic use of alprazolam and lorazepam.
TLDR
Persistent use of alprazolam/lorazepam for therapeutic purposes did not represent abuse or addiction as the terms are usually understood, and a substantial proportion of these patients may be receiving appropriate maintenance therapy for a chronic psychiatric condition. Expand
Survival analytic approach to long‐term prescription of benzodiazepine hypnotics
TLDR
The results indicated that 20% of patients who had started prescriptions for BZ hypnotics had the potential to induce dependence, and a low dose was considered to be associated with an ability to be free from Bz hypnotics in an early period. Expand
Severity of alprazolam dependence and associated features among long-term alprazolam users from psychiatric outpatient clinics in Taiwan.
TLDR
Doctors should closely monitor the severity of alprazolam dependence among long-term users, especially patients' levels of depression, beliefs in the necessity of al prazol am treatment, and their concerns over the adverse consequences of continued treatment with alpazolam. Expand
The role of alprazolam for the treatment of panic disorder in Australia
TLDR
Alprazolam has shown efficacy for control of PD symptoms, particularly in short-term controlled clinical trials, but is no longer recommended as a first-line pharmacological treatment due to concerns about the risks of developing tolerance, dependence and abuse potential. Expand
Long-term codeine use is associated with depressive symptoms.
TLDR
Data suggest that dysphoric mood states may be significant in maintaining long-term codeine use, and specifically on the Symptom Checklist-90 subscales. Expand
Characteristics of dependent and nondependent regular users of codeine.
TLDR
It was showed that dependence is associated with the regular use of codeine and there is a need to identify individuals experiencing problems with their codeine use and to develop optimal prevention and treatment strategies. Expand
Long-term benzodiazepine use: factors of importance and the development of individual use patterns over time--a 13-year follow-up in a Swedish community.
TLDR
Age, age, a combined use of tranquilizers and hypnotics, and prescriptions from more than one of the prescriber categories studied (i.e. doctors working at health centers, hospital doctors, and private doctors) were significant factors in frequent or daily use. Expand
Reducing the use of benzodiazepines in general practice
TLDR
The use of benzodiazepines has fallen steadily since the 1970s, and they are now often regarded as suitable only for short term use, if they have a use at all. Expand
Clinical pharmacology, clinical efficacy, and behavioral toxicity of alprazolam: a review of the literature.
TLDR
An exhaustive review of the literature showed that alprazolam is significantly superior to placebo, and is at least equally effective in the relief of symptoms as tricyclic antidepressants (TCAs) such as imipramine. Expand
A controlled trial of ondansetron, a 5-HT3 antagonist, in benzodiazepine discontinuation.
TLDR
Ondansetron had no significant effects on severity of withdrawal symptoms or levels of anxiety, and high placebo response may have prevented detection of an ondansetrons effect. Expand
...
1
2
3
...