Characteristics necessary for an interconvertible enzyme cascade to generate a highly sensitive response to an effector.

@article{Crdenas1989CharacteristicsNF,
  title={Characteristics necessary for an interconvertible enzyme cascade to generate a highly sensitive response to an effector.},
  author={Mar{\'i}a Luz C{\'a}rdenas and Athel Cornish-Bowden},
  journal={The Biochemical journal},
  year={1989},
  volume={257 2},
  pages={339-45}
}
A monocyclic interconvertible enzyme cascade, in which active and inactive states of an enzyme are interconverted by two opposing enzyme-catalysed reactions, does not necessarily produce a greater degree of sensitivity to an effector than one could expect from direct interaction between effector and target reaction. On the contrary, a cascade in which an effector acts on one of the enzymes catalysing the interconversion reactions by altering the apparent value of its specificity constant will… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
22 Citations
1 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

References

Publications referenced by this paper.

Catalytic effects in interconvertible enzyme

  • A. Goldbeter, D. E. Koshland, Jr.
  • Proc. Nati. Acad. Sci. U.S.A
  • 1989

Similar Papers

Loading similar papers…