Characteristics and genetic control of NK-cell-mediated cytotoxicity activated by naturally acquired infection in the mouse.

@article{Clark1979CharacteristicsAG,
  title={Characteristics and genetic control of NK-cell-mediated cytotoxicity activated by naturally acquired infection in the mouse.},
  author={Edward A. Clark and Peter H. Russell and M Egghart and M A Horton},
  journal={International journal of cancer},
  year={1979},
  volume={24 5},
  pages={688-99}
}
Most and perhaps all natural-cell-mediated cytotoxicity (NCMC) may be activated by a response to exogenous infections. Specific-pathogen-free (SPF) mice have little or no natural killer (NK) cell activity, but when they are relocated in conventional conditions, they develop strong NCMC within 2 to 3 days. Unlike other SPF animals, hypothymic nude mice display good NCMC which is further augmented upon their entry into a pathogenic environment. The ontogeny, genetic control and other features of… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
15 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…