Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes.

@article{Hollenberg2002CharacteristicsAC,
  title={Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes.},
  author={Paul F. Hollenberg},
  journal={Drug metabolism reviews},
  year={2002},
  volume={34 1-2},
  pages={17-35}
}
The modification of the enzymatic activity of the cytochrome P450 (CYP) enzymes by inhibition, induction, or activation is of great interest to enzymologists, pharmacologists, and chemists who are interested in mechanisms relating to these three effectors of enzyme activity. When the activity of a CYP is modified in vivo in humans, these effects are a major concern for clinicians and patients due to the potential for these alterations to greatly change the metabolism of the drug substrate(s… CONTINUE READING