Characteristic generated alterations of autoantibody patterns in idiopathic thrombocytopenic purpura.

@article{Sundblad1997CharacteristicGA,
  title={Characteristic generated alterations of autoantibody patterns in idiopathic thrombocytopenic purpura.},
  author={A Sundblad and Carolina Ferreira and Alberto N{\'o}brega and Matthias Haury and Erica Ferreira and Francine P{\'a}dua and Ant{\'o}nio Coutinho},
  journal={Journal of autoimmunity},
  year={1997},
  volume={10 2},
  pages={193-201}
}
Using a Western blot technique that allows quantitative detection of antibody reactivities to a large number of antigens, serum IgG and IgM antibody repertoires were compared in a group of 19 patients with a diagnosis of idiopathic thrombocytopenic purpura (ITP) and respective healthy controls. The results show that, irrespective of the duration of thrombocytopenia, age of the patients, and type of therapy, all ITP donors share characteristic alterations of serum antibody reactivity patterns on… CONTINUE READING

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