Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model

@article{Liu2009CharacteristicGE,
  title={Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model},
  author={Yue-Fang Liu and Bin-Shan Zha and Hui-lin Zhang and Xiao-Jing Zhu and Yuhua Li and Jin Zhu and Xiao-hong Guan and Zhen-qing Feng and Jian-Ping Zhang},
  journal={Journal of Experimental & Clinical Cancer Research : CR},
  year={2009},
  volume={28},
  pages={107 - 107}
}
BACKGROUND Liver cancer is a heterogeneous disease in terms of etiology, biologic and clinical behavior. Very little is known about how many genes concur at the molecular level of tumor development, progression and aggressiveness. To explore the key genes involved in the development of liver cancer, we established a rat model induced by diethylnitrosamine to investigate the gene expression profiles of liver tissues during the transition to cirrhosis and carcinoma. METHODS A rat model of liver… CONTINUE READING
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