Characteristic features and biotechnological applications of cross-linked enzyme aggregates (CLEAs)

@inproceedings{Sheldon2011CharacteristicFA,
  title={Characteristic features and biotechnological applications of cross-linked enzyme aggregates (CLEAs)},
  author={Roger A Sheldon},
  booktitle={Applied Microbiology and Biotechnology},
  year={2011}
}
Cross-linked enzyme aggregates (CLEAs) have many economic and environmental benefits in the context of industrial biocatalysis. They are easily prepared from crude enzyme extracts, and the costs of (often expensive) carriers are circumvented. They generally exhibit improved storage and operational stability towards denaturation by heat, organic solvents, and autoproteolysis and are stable towards leaching in aqueous media. Furthermore, they have high catalyst productivities (kilograms product… CONTINUE READING

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