Characteristic Clinicopathological Features of the Types of Intraductal Papillary-Mucinous Neoplasms of the Pancreas

@article{Ishida2007CharacteristicCF,
  title={Characteristic Clinicopathological Features of the Types of Intraductal Papillary-Mucinous Neoplasms of the Pancreas},
  author={Masaharu Ishida and Shin‐ichi Egawa and Takeshi Aoki and Naoaki Sakata and Yukio Mikami and Fuyuhiko Motoi and Tadayoshi Abe and Shoji Fukuyama and Makoto Sunamura and Michiaki Unno and Takuya Moriya and Akira Horii and Toru Furukawa},
  journal={Pancreas},
  year={2007},
  volume={35},
  pages={348-352}
}
Objectives: Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas encompasses a spectrum of neoplasms with both morphological and immunohistochemical variations of mucin glycoproteins. Recently, a consensus nomenclature and criteria were histologically defined for classifying these variants of IPMNs into gastric, intestinal, pancreatobiliary, and oncocytic types. The purpose of this study was to determine associations between the histological types and clinicopathological features in… 
Intraductal Papillary-Mucinous Neoplasms of the Gastric and Intestinal Types May Have Less Malignant Potential Than the Pancreatobiliary Type
TLDR
Intraductal papillary-mucinous neoplasm of the gastric and intestinal types may have less malignant potential than that of the pancreatobiliary type.
Prognostic value of histological subtype in intraductal papillary mucinous neoplasm of the pancreas
TLDR
Histological subtype had limited prognostic value in patients with IPMNs, and the main prognostic factor for patients with invasive IPMNs was the lymph-node status, so the association between nerve invasion and overall survival lost statistical significance after multivariate analysis.
Evaluation of Clinical Meaning of Histological Subtypes of Intraductal Papillary Mucinous Neoplasm of the Pancreas
TLDR
Although histological subtypes are associated with the degree of dysplasia, histology subtypes have limited prognostic value for pancreatic IPMNs.
Distinct patterns of peritumoral histological findings in subtypes of intraductal papillary mucinous neoplasms of the pancreas.
TLDR
Differences suggest the possibility that each subtype of IPMNs has a distinct mechanism from an early stage of tumor progression, which is reflected in the properties of the peritumoral stroma.
Preoperative Histological Subtype Classification of Intraductal Papillary Mucinous Neoplasms (IPMN) by Pancreatic Juice Cytology With MUC Stain
TLDR
Preoperative PJC with MUC stain proved to be highly reliable for identifying the histological subtype of IPMN and may provide useful information for deciding surgical indication.
Frequency of subtypes of biliary intraductal papillary mucinous neoplasm and their MUC1, MUC2, and DPC4 expression patterns differ from pancreatic intraductal papillary mucinous neoplasm.
TLDR
Histopathologic subtypes and type-specific MUC expression patterns of B-IPMN resemble those of P-IP MN, providing additional support that B- IPMN is a unique entity with similarities to main duct P-ipMN.
Clinicopathologic Features of Intraductal Papillary Neoplasm of the Bile Duct According to Histologic Subtype
TLDR
Gastric and intestinal types of IPN-B have similar clinical characteristics compared with the pancreaticobiliary type, which has a worse prognosis.
Intraductal oncocytic papillary neoplasms of the pancreas and bile ducts: a description of five new cases and review based on a systematic survey of the literature
TLDR
There are no reliable criteria other than histopathological picture and K-ras gene status to differentiate IOPN from IPMN, and several differences in the clinical and biological profile between IOPn and IPMN exist, but they are of quantitative rather than of qualitative nature.
Prognosis of invasive intraductal papillary mucinous neoplasm depends on histological and precursor epithelial subtypes
TLDR
Analysis of these subtypes indicates that the background epithelium plays an equally, if not more, important role in defining the biology and prognosis of invasive IPMNs, and arise from different epithelial subtypes.
Intraductal Papillary Mucinous Neoplasms Often Contain Epithelium From Multiple Subtypes and/or Are Unclassifiable
Pancreatic intraductal papillary mucinous neoplasms (IPMNs) are subclassified into gastric, intestinal, pancreatobiliary, and oncocytic subtypes based on histologic features. The WHO classification
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References

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TLDR
A consensus nomenclature and criteria for classifying variants as distinctive IPMN subtypes including gastric type, intestinal type, pancreatobiliary type, and oncocytic type are defined and can be used for further analyses of the clinicopathological significance of the variations of IPMN.
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TLDR
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TLDR
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TLDR
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