Characterisation of the affinity of different anabolics and synthetic hormones to the human androgen receptor, human sex hormone binding globulin and to the bovine progestin receptor

@article{Bauer2000CharacterisationOT,
  title={Characterisation of the affinity of different anabolics and synthetic hormones to the human androgen receptor, human sex hormone binding globulin and to the bovine progestin receptor},
  author={E. Bauer and A. Daxenberger and T. Petri and H. Sauerwein and H. H. Meyer},
  journal={APMIS},
  year={2000},
  volume={108}
}
  • E. Bauer, A. Daxenberger, +2 authors H. H. Meyer
  • Published 2000
  • Biology, Medicine
  • APMIS
  • For the steroidal growth promoters trenbolone acetate (TBA) and melengestrol acetate (MGA) neither the complete spectrum of biological activities nor the potential endocrine disrupting activity of their excreted metabolites in the environment is fully understood. The potency of these substances in [3H]‐dihydrotestosterone ([3H]‐DHT) displacement from the recombinant human androgen receptor (rhAR) and from human sex‐hormone binding globulin (hSHBG) was evaluated. In addition, the potency for [3H… CONTINUE READING
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    References

    SHOWING 1-10 OF 43 REFERENCES
    5α-Reduction of norethisterone enhances its binding affinity for androgen receptors but diminishes its androgenic potency
    • 33
    Binding of progestagens to receptor proteins in MCF-7 cells.
    • 84