Characterisation of the abiotic degradation pathways of oxytetracyclines in soil interstitial water using LC-MS-MS.

@article{HallingSrensen2003CharacterisationOT,
  title={Characterisation of the abiotic degradation pathways of oxytetracyclines in soil interstitial water using LC-MS-MS.},
  author={Bent Halling-S\orensen and Anne Kruse Lykkeberg and Flemming Ingerslev and P. S. Blackwell and Jette Tj\ornelund},
  journal={Chemosphere},
  year={2003},
  volume={50 10},
  pages={1331-42}
}
The fate of oxytetracyclines (OTCs) in soil interstitial water was investigated and the structure of a number of degradation products elucidated in a time-related experiment. A previously developed separation method for LC-MS-MS able to base separate and quantify OTC and three of its epimers and degradation products was applied. Compounds detected were 4-epi-oxytetracycline (EOTC) (t(R)=3.0 min), OTC (t(R)=4.4 min), alpha-apo-oxytetracycline (alpha-apo-OTC) (t(R)=11.4 min) and beta-apo… CONTINUE READING