Characterisation of atypical enteropathogenic E. coli strains of clinical origin

  title={Characterisation of atypical enteropathogenic E. coli strains of clinical origin},
  author={Sharon M. Tennant and Marija Tauschek and Kristy I Azzopardi and Andrea K Bigham and Vicki R. Bennett-Wood and Elizabeth L Hartland and Weihong Qi and Thomas S. Whittam and Roy M Robins-Browne},
  booktitle={BMC Microbiology},
Enteropathogenic E. coli (EPEC) is a prominent cause of diarrhoea, and is characterised in part by its carriage of a pathogenicity island: the locus for enterocyte effacement (LEE). EPEC is divided into two subtypes according to the presence of bundle-forming pili (BFP), a fimbrial adhesin that is a virulence determinant of typical EPEC (tEPEC), but is absent from atypical EPEC (aEPEC). Because aEPEC lack BFP, their virulence has been questioned, as they may represent LEE-positive Shiga toxin… CONTINUE READING


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