Characterisation of an extract and fractions of Azadirachta indica flower on cholesterol lowering property and intestinal motility

  title={Characterisation of an extract and fractions of Azadirachta indica flower on cholesterol lowering property and intestinal motility},
  author={Acharaporn Duangjai and Nitra Nuengchamnong and Learn‐Han Lee and Bey‐Hing Goh and Surasak Saokaew and Nungruthai Suphrom},
  journal={Natural Product Research},
  pages={1491 - 1494}
Abstract Azadirachta indica has long been used in traditional medicine. This study focused on isolation and characterisation of active ingredients in the extract, its fractions (NF-EA, NF-AQ, NF-G) and its effect on the cholesterol absorption activity. The NF-EA fraction was identified by marker compounds by LC-ESI-QTOF/MS. Cholesterol absorption activity was performed by measuring the solubility and size of cholesterol micelles. The intestinal motility was also examined by isolated rat’s ileum… 
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Effect of Neem (Azadirachta indica L.) on Lipid Oxidation in Raw Chilled Beef Patties
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The cogent data on the anticancer biology of products from A. indica deserve multi-institutional clinical trials as early as possible, so the prospects of relatively cheaper cancer drugs could be brighter, particularly for the under-privileged cancer patients of the world.
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This review summarises the wide range of pharmacological activities of neem leaf and its constituents, demonstrated to exhibit immunomodulatory, anti-inflammatory, antihyperglycaemic, antiulcer, antimalarial, antifungal, antibacterial, antiviral, antioxidant, antimutagenic and anticarcinogenic properties.
Calcium-antagonist effect of quercetin and its relation with the spasmolytic properties of Psidium guajava L.
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Anti-Hyperglycemic And Antidyslipidemic Potential Of Azadirachta indica Leaf Extract In STZ- Induced Diabetes Mellitus
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Luteolin and Quercetin Affect the Cholesterol Absorption Mediated by Epithelial Cholesterol Transporter Niemann–Pick C1-Like 1 in Caco-2 Cells and Rats
Luteolin and quercetin reduce high blood cholesterol levels by specifically inhibiting intestinal cholesterol absorption mediated by NPC1L1, and this work suggests that polyphenols inhibit intestinal transport of cholesterol.