Characterisation of a putative glutamate 5-kinase from Leishmania donovani.

@article{Sienkiewicz2018CharacterisationOA,
  title={Characterisation of a putative glutamate 5-kinase from Leishmania donovani.},
  author={Natasha Sienkiewicz and Han B. Ong and Alan H. Fairlamb},
  journal={The FEBS journal},
  year={2018}
}
Previous metabolic studies have demonstrated that leishmania parasites are able to synthesise proline from glutamic acid and threonine from aspartic acid. The first committed step in both biosynthetic pathways involves an amino acid kinase, either a glutamate 5-kinase (G5K; EC2.7.2.11) or an aspartokinase (EC2.7.2.4). Bioinformatic analysis of multiple… CONTINUE READING