Characterisation of a membrane-bound serine-specific casein kinase isolated from lactating guinea-pig mammary gland.


Serine-specific and threonine-specific casein kinase activities have been identified in a Golgi-enriched membrane fraction isolated from the lactating guinea-pig mammary gland. The serine-specific casein kinase has been purified 2000-fold by affinity chromatography on ATP-agarose. The enzyme has an estimated Mr of 100000 as determined by sucrose gradient… (More)


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