Characterisation of a human homologue of a yeast cell division cycle gene, MCM6, located adjacent to the 5' end of the lactase gene on chromosome 2q21.

@article{Harvey1996CharacterisationOA,
  title={Characterisation of a human homologue of a yeast cell division cycle gene, MCM6, located adjacent to the 5' end of the lactase gene on chromosome 2q21.},
  author={Clare B Harvey and Yangmeng Wang and Dalila Darmoul and Alan D. Phillips and Ned Mantei and Dallas M Swallow},
  journal={FEBS letters},
  year={1996},
  volume={398 2-3},
  pages={135-40}
}
Four exons of a human homologue of a yeast cell division cycle gene (MCM6/mis5, which is thought to encode a DNA replication licensing factor) have been identified 3.3 kb upstream from the start of transcription of the intestinal lactase gene on human chromosome 2q21, initially by similarity to a rat 'intestinal crypt-cell replication factor'. RT-PCR analysis shows, that unlike lactase, MCM6 is not restricted in its tissue distribution and does not show person-to-person variation in the level… CONTINUE READING
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