Characterisation of a Transport System for Cystine in Leucocytes Lysosomal Membranes

Abstract

Normal leucocyte lysosomal membranes are able to transport cystine by a saturable process exhibiting efflux (T) and Counter-transport (CT). Leucocyte lysosomes from cystinotic patients lack this carrier mediated transport and thus store cystine. In order to establish whether T and CT are mediated by the same site, the effect of proteolytic enzymes, ATP… (More)
DOI: 10.1203/00006450-198510000-00038

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