Characterisation of Ercc1 deficiency in the liver and in conditional Ercc1-deficient primary hepatocytes in vitro.

Abstract

The ERCC1/XPF complex is responsible for incision at the 5' side of the lesion during nucleotide excision repair and is also involved in homologous recombination and interstrand cross-link repair. The aim of the current study was to set up a better model for examination of Ercc1 deficiency in the murine liver and to determine the DNA lesions responsible for… (More)

Topics

Cite this paper

@article{Kirschner2007CharacterisationOE, title={Characterisation of Ercc1 deficiency in the liver and in conditional Ercc1-deficient primary hepatocytes in vitro.}, author={Kristina Kirschner and Rajinder Singh and Sandrine Prost and David W. Melton}, journal={DNA repair}, year={2007}, volume={6 3}, pages={304-16} }