Characterisation of Aspergillus niger prolyl aminopeptidase

  title={Characterisation of Aspergillus niger prolyl aminopeptidase},
  author={Dani{\"e}lle E. J. W. Basten and Antoine P. H. A. Moers and Albert J. J. van. Ooyen and Peter J. Schaap},
  journal={Molecular Genetics and Genomics},
We have cloned a gene (papA) that encodes a prolyl aminopeptidase from Aspergillus niger. Homologous genes are present in the genomes of the Eurotiales A. nidulans, A. fumigatus and Talaromyces emersonii, but the gene is not present in the genome of the yeast Saccharomyces cerevisiae. Cell extracts of strains overexpressing the gene under the control of its own promoter showed a fourfold to sixfold increase in prolyl aminopeptidase activity, but no change in phenylalanine or leucine… CONTINUE READING
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Handbook of proteolytic enzymes

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