Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques.

@article{Nilsson1999CharacterisationO5,
  title={Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques.},
  author={Th{\'e}r{\`e}se Nilsson and Jenny Longmore and Duncan E Shaw and Emil Pantev and Jonathan A. Bard and Theresa A. Branchek and Lars Edvinsson},
  journal={European journal of pharmacology},
  year={1999},
  volume={372 1},
  pages={49-56}
}
5-Hydroxytryptamine (5-HT) can produce both vasoconstrictor and vasorelaxant effects in human coronary arteries and the response to 5-HT can be influenced by the presence of disease. The aim of the present study was to elucidate the 5-HT receptor subtypes responsible for mediating 5-HT-evoked contraction of human coronary arteries using pharmacological, molecular and immunocytochemical approaches. Normal human coronary arteries, with intact endothelium, were mounted in tissue baths, and the… CONTINUE READING

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