Characterisation and expression of the Fasciola gigantica cathepsin L gene.

@article{Yamasaki2002CharacterisationAE,
  title={Characterisation and expression of the Fasciola gigantica cathepsin L gene.},
  author={Hiroshi Yamasaki and Reiko Mineki and Kimie Murayama and Akira Ito and Takashi Aoki},
  journal={International journal for parasitology},
  year={2002},
  volume={32 8},
  pages={
          1031-42
        }
}
The gene structure of a cathepsin L from Fasciola gigantica was characterised. The gene spans approximately 2.0 kb and comprises four exons and three introns and is a compact gene as in the cases of crustaceous and platyhelminth cathepsins L. Southern blot analysis suggested that a few copies of the genes are sparsely organised in the genome. Of the three intron insertion positions, two of which are in the same position as in the mammalian cathepsin L gene. Phylogenetic analysis revealed that F… CONTINUE READING
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