Chapter 4 – The Heart

  title={Chapter 4 – The Heart},
  author={David A. Rubenstein and Wei Yin and Mary D Frame},

A system for the monitoring of sleep-related parameters based on inertial measurement units

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A fluid-mechanical study of the closure of heart valves

The fluid mechanics of heart-valve motion is investigated experimentally and theoretically. From the experiments, it is found that the principal mechanism ensuring optimal mitral-valve closure is the

Endothelial cell regulation of contractility of the heart.

Two endothelial cell-dependent systems exist for regulating contractile efficiency: One involving endothelin appears to optimize the contraction for efficiency; the other, the beta-adrenergic-mediated system, optimizes for power.

Fluid mechanics of a model mitral valve and left ventricle.

  • B. Bellhouse
  • Medicine, Engineering
    Cardiovascular research
  • 1972
The effect of atrial systole on valve closure was studied experimentally and theoretically and showed to be due to a ring-vortex occupying the left ventricle together with flow deceleration through the mitral ring during the latter part of diastole.

Systolic Mechanical Properties of the Left Ventricle: Effects of Volume and Contractile State

The view that elasticity-or the end-systolic pressure-volume relationship- serves in a given heart to quantify contractility is supported.

Load Independence of the Instantaneous Pressure‐Volume Ratio of the Canine Left Ventricle and Effects of Epinephrine and Heart Rate on the Ratio

It is concluded that E(t), represented by Emax and Tmax, explicitly reflects the ventricular contractility.

Calcium release from cardiac sarcoplasmic reticulum.

  • S. Winegrad
  • Biology, Medicine
    Annual review of physiology
  • 1982
Attention is focused on specific properties of the reticulum that are related to its integrated function within the cardiac cell, in particular the triggering mechanism for release of calcium from the Reticulum, changes in the properties of, during the cardiac cycle, and the modulation of sarcoplasmic Ca during a normal contraction of it myocardial cell.

Instantaneous Pressure‐Volume Relationships and Their Ratio in the Excised, Supported Canine Left Ventricle

The present study on an excised, supported canine heart preparation indicates that the thesis on E(t) is also valid for either totally isovolumic or auxobaric beats.

Mechanics of active contraction in cardiac muscle: Part II--Cylindrical models of the systolic left ventricle.

Models of contracting ventricular myocardium were used to study the effects of different assumptions concerning active tension development on the distributions of stress and strain in the equatorial

End‐Systolic Pressure Determines Stroke Volume from Fixed End‐Diastolic Volume in the Isolated Canine Left Ventricle under a Constant Contractile State

Results were interpreted to indicate that, when ejection ends at the end of systole, stroke volume of the ventricle with a given end-diastolic volume is determined predominantly by the end-systolic pressure rather than by the entire systolic courses of the pressure and volume.