Corpus ID: 46610816

Chapter 3 Methods for Predicting RNA Secondary Structure

@inproceedings{Aigner2012Chapter3M,
  title={Chapter 3 Methods for Predicting RNA Secondary Structure},
  author={Kornelia Aigner and F. Dre{\ss}en and G. Steger},
  year={2012}
}
The formation of RNA structure is a hierarchical process: the secondary structure builds up by thermodynamically favorable stacks of base pairs (helix formation) and unfavorable loops (non-Watson–Crick base pairs; hairpin, internal, and bulge loops; junctions). The tertiary structure folds on top of the thermodynamically optimal or close-to-optimal secondary structure by formation of pseudoknots, base triples, and/or stacking of helices. In this chapter, we will concentrate on available… CONTINUE READING

Figures and Tables from this paper

References

SHOWING 1-10 OF 119 REFERENCES
Correlation of RNA secondary structure statistics with thermodynamic stability and applications to folding.
  • 26
Accurate SHAPE-directed RNA structure determination
  • 544
  • PDF
Predicting structures and stabilities for H-type pseudoknots with interhelix loops.
  • 86
  • PDF
RNAstructure: software for RNA secondary structure prediction and analysis
  • 1,079
  • Highly Influential
Assembly mechanisms of RNA pseudoknots are determined by the stabilities of constituent secondary structures
  • 85
  • PDF
Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure.
  • 3,576
  • PDF
How RNA folds.
  • 773
Predicting thermodynamic properties of RNA.
  • 300
Predicting RNA pseudoknot folding thermodynamics
  • 140
  • Highly Influential
  • PDF