Chapter 2 Integrin Structure and Function

  title={Chapter 2 Integrin Structure and Function},
  author={Manakan Betsy Srichai and Roy Zent},
Abstract Integrins are a large family of heterodimeric glycoprotein receptors first discovered over twenty years ago. They exist as two noncovalently bound aand bsubunits that function as adhesion molecules and play key roles in many biological processes including actin cytoskeleton organization and transduction of intracellular signals regulating cellular functions. Integrins bind a variety of extracellular matrices including collagens and laminins. The phenotypes observed from the generation… CONTINUE READING
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