Chapter 14: Electron microscopy of hydrated samples.


Conventional electron microscopy offers a substantial resolution advantage over light microscopy, but requires difficult and often destructive preparation techniques. Recent advances in electron microscopy allow for imaging of hydrated samples, retaining the resolution advantage while removing the difficulty in preparation. Two new techniques, environmental scanning electron microscopy and wet electron microscopy offer this advantage, allowing for new possibilities in biological imaging.

DOI: 10.1016/S0091-679X(08)00614-6


Citations per Year

165 Citations

Semantic Scholar estimates that this publication has 165 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Timp2008Chapter1E, title={Chapter 14: Electron microscopy of hydrated samples.}, author={Winston Timp and Paul Matsudaira}, journal={Methods in cell biology}, year={2008}, volume={89}, pages={391-407} }