Corpus ID: 34609140

Chapter 1 The Molecular Frame of Pancreatic Carcinogenesis

@inproceedings{Hessmann2014Chapter1T,
  title={Chapter 1 The Molecular Frame of Pancreatic Carcinogenesis},
  author={E. Hessmann and Sandra Baumgart and N. M. Chen and S. Singh and G. Singh and A. K{\"o}nig and A. Neesse and V. Ellenrieder},
  year={2014}
}
Annually, approximately 43,140 people are diagnosed (incidence 10-12/100000) with pancre‐ atic ductal adenocarcinoma (PDAC) in the United States and the mortality rate of 36800 almost equals this number [1]. PDAC ranks fourth on the list of cancer-related causes of death and despite extensive scientific and clinical effort, the prognosis of this exceptionally lethal disease has not improved significantly over the past decades [2]. Surgical resection, for which only a minority (less than 20%) of… Expand

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