Chapter 1 NMDA Receptors and Brain Development

  title={Chapter 1 NMDA Receptors and Brain Development},
  author={Rebecca C. Ewald and Hollis T. Cline},
More than 20 years have passed since the discovery that NMDAR-mediated synaptic activity is important for the functional development of sensory brain circuits [1] by specifically regulating the refinement of sensory topographic maps [2]. Since then we have learned in great detail how this receptor shapes the development of neurons and neuronal circuits. The diversity of NMDAR subunits and their unique developmental and spatial expression patterns add levels of complexity to the role of the… CONTINUE READING
7 Citations
96 References
Similar Papers


Publications citing this paper.


Publications referenced by this paper.
Showing 1-10 of 96 references

D-aspartate receptor subunit genes in the zebrafish

  • RJ Dunn, D Bottai, L. Maler
  • Dev. Dyn. 2005;234:756
  • 2008

Differential roles of NR2A and NR2B-containing NMDARs in LTP and LTD in the CA1 region of two-week old rat hippocampus

  • TE Bartlett
  • depression. Neuropharmacology
  • 2007

Differential roles of NR2A and NR2B-containing NMDARs in cortical long-term potentiation and long-term depression

  • PV Massey
  • J. Neurosci. 2004;24:7821
  • 2006

Similar Papers

Loading similar papers…