Chaperoning stem cells: a role for heat shock proteins in the modulation of stem cell self-renewal and differentiation?

@article{Prinsloo2009ChaperoningSC,
  title={Chaperoning stem cells: a role for heat shock proteins in the modulation of stem cell self-renewal and differentiation?},
  author={Earl Prinsloo and Mokgadi M Setati and Victoria Mary Longshaw and Gregory L Blatch},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2009},
  volume={31 4},
  pages={
          370-7
        }
}
Self-renewal and differentiation of stem cells are tightly regulated processes subject to intrinsic and extrinsic signals. Molecular chaperones and co-chaperones, especially heat shock proteins (Hsp), are ubiquitous molecules involved in the modulation of protein conformational and complexation states. The function of Hsp, which are typically associated with stress response and tolerance, is well characterized in differentiated cells, while their role in stem cells remains unclear. It appears… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 35 CITATIONS

Hspa9 is required for pronephros specification and formation in Xenopus laevis.

  • Developmental dynamics : an official publication of the American Association of Anatomists
  • 2015
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Similar Papers

Loading similar papers…