Chaperonin-mediated protein folding: fate of substrate polypeptide
@article{Fenton2003ChaperoninmediatedPF, title={Chaperonin-mediated protein folding: fate of substrate polypeptide}, author={Wayne A. Fenton and Arthur L. Horwich}, journal={Quarterly Reviews of Biophysics}, year={2003}, volume={36}, pages={229 - 256} }
1. Chaperonin action – an overview 230 2. Polypeptide binding – an essential action 235 3. Recognition of non-native polypeptide – role of hydrophobicity 236 4. Crystallographic analyses of peptide binding 237 5. Topology and secondary and tertiary structure of bound substrate polypeptide – fluorescence, hydrogen exchange and NMR studies 239 6. Binding by GroEL associated with a putative unfolding action 242 7. A potential action of substrate unfolding driven by ATP/GroES binding 245 8. Folding…
156 Citations
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