Chaperonin-mediated protein folding: fate of substrate polypeptide

@article{Fenton2003ChaperoninmediatedPF,
  title={Chaperonin-mediated protein folding: fate of substrate polypeptide},
  author={W. Fenton and A. Horwich},
  journal={Quarterly Reviews of Biophysics},
  year={2003},
  volume={36},
  pages={229 - 256}
}
1. Chaperonin action – an overview 230 2. Polypeptide binding – an essential action 235 3. Recognition of non-native polypeptide – role of hydrophobicity 236 4. Crystallographic analyses of peptide binding 237 5. Topology and secondary and tertiary structure of bound substrate polypeptide – fluorescence, hydrogen exchange and NMR studies 239 6. Binding by GroEL associated with a putative unfolding action 242 7. A potential action of substrate unfolding driven by ATP/GroES binding 245 8. Folding… Expand
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