Chaperone-mediated autophagy in protein quality control.

  title={Chaperone-mediated autophagy in protein quality control.},
  author={Esperanza Arias and Ana Mar{\'i}a Cuervo},
  journal={Current opinion in cell biology},
  volume={23 2},
Chaperone-mediated autophagy is a selective mechanism for degradation of soluble cytosolic proteins in lysosomes that distinguishes itself from other autophagic pathways by the selectivity with which CMA substrates are targeted for degradation. The recent molecular dissection of this autophagic pathway and the development of experimental models with… CONTINUE READING