Chaperone function and chaperone overload in the aged. A preliminary analysis.

@article{Nardai2002ChaperoneFA,
  title={Chaperone function and chaperone overload in the aged. A preliminary analysis.},
  author={G{\'a}bor Nardai and P{\'e}ter Csermely and Csaba S{\"o}ti},
  journal={Experimental gerontology},
  year={2002},
  volume={37 10-11},
  pages={1257-62}
}
Chaperones have an important role in the repair of proteotoxic damage, which is greatly increased in aged subjects. Chaperone levels and expression were subject of numerous studies in aged organisms. However, there were only very few attempts to measure chaperone activity in aged animals. Here, we report our initial studies showing a decreased chaperone… CONTINUE READING