Channelrhodopsin-2 and optical control of excitable cells

@article{Zhang2006Channelrhodopsin2AO,
  title={Channelrhodopsin-2 and optical control of excitable cells},
  author={Feng Zhang and Li-Ping Wang and Edward S. Boyden and Karl Deisseroth},
  journal={Nature Methods},
  year={2006},
  volume={3},
  pages={785-792}
}
Electrically excitable cells are important in the normal functioning and in the pathophysiology of many biological processes. These cells are typically embedded in dense, heterogeneous tissues, rendering them difficult to target selectively with conventional electrical stimulation methods. The algal protein Channelrhodopsin-2 offers a new and promising solution by permitting minimally invasive, genetically targeted and temporally precise photostimulation. Here we explore technological issues… Expand

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