Channelopathies from mutations in the cardiac sodium channel protein complex.

Abstract

The cardiac sodium current underlies excitability in heart, and inherited abnormalities of the proteins regulating and conducting this current cause inherited arrhythmia syndromes. This review focuses on inherited mutations in non-pore forming proteins of sodium channel complexes that cause cardiac arrhythmia, and the deduced mechanisms by which they affect… (More)
DOI: 10.1016/j.yjmcc.2013.03.017

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Cite this paper

@article{Adsit2013ChannelopathiesFM, title={Channelopathies from mutations in the cardiac sodium channel protein complex.}, author={Graham S Adsit and R. Vaidyanathan and Carla M Galler and John W. Kyle and Jonathan C. Makielski}, journal={Journal of molecular and cellular cardiology}, year={2013}, volume={61}, pages={34-43} }