Channel and substrate zone two-dimensional resolution for chemiluminescent multiplex immunoassay.

@article{Fu2007ChannelAS,
  title={Channel and substrate zone two-dimensional resolution for chemiluminescent multiplex immunoassay.},
  author={Zhifeng Fu and Zhanjun Yang and J Tang and Hong Liu and Feng Yan and Huangxian Ju},
  journal={Analytical chemistry},
  year={2007},
  volume={79 19},
  pages={7376-82}
}
A two-dimensional resolution system of channels and substrate zones was proposed for multiplex immunoassay performed with a designed multichannel chemiluminescent (CL) detection device coupled with a single photomultiplier. Using carcinoma antigen 125 (CA 125), carcinoma antigen 153 (CA 153), carcinoma antigen 199 (CA 199), and carcinoembryonic antigen (CEA) as two couples of model analytes, two couples of capture antibodies were immobilized in two channels, respectively. With a sandwich format… CONTINUE READING