Changing responsiveness of developing midbrain dopaminergic neurons for extracellular growth factors.

@article{Engele1998ChangingRO,
  title={Changing responsiveness of developing midbrain dopaminergic neurons for extracellular growth factors.},
  author={Juergen Engele},
  journal={Journal of neuroscience research},
  year={1998},
  volume={51 4},
  pages={508-16}
}
Numerous purified growth factors as well as yet-unidentified neurotrophic activities within mesencephalic glia support the survival of dopaminergic neurons. To further characterize the functional role of these multiple growth factor influences in dopaminergic cell development, various purified growth factors as well as mesencephalic glial-conditioned medium (CM) were screened for effects on dopaminergic cell survival and glial numbers in serum-free low density cultures of the dissociated… CONTINUE READING