Changing properties of GABA(A) receptor-mediated signaling during early neocortical development.

@article{Owens1999ChangingPO,
  title={Changing properties of GABA(A) receptor-mediated signaling during early neocortical development.},
  author={David F. Owens and Xinhuai Liu and Arnold R Kriegstein},
  journal={Journal of neurophysiology},
  year={1999},
  volume={82 2},
  pages={570-83}
}
Evidence from several brain regions suggests gamma-aminobutyric acid (GABA) can exert a trophic influence during development, expanding the role of this amino acid beyond its function as an inhibitory neurotransmitter. Proliferating precursor cells in the neocortical ventricular zone (VZ) express functional GABA(A) receptors as do immature postmigratory neurons in the developing cortical plate (CP); however, GABA(A) receptor properties in these distinct cell populations have not been compared… CONTINUE READING

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