Changing prognostic significance of tumor stage and nodal stage in patients with squamous cell carcinoma of the oropharynx in the human papillomavirus era

@article{Keane2015ChangingPS,
  title={Changing prognostic significance of tumor stage and nodal stage in patients with squamous cell carcinoma of the oropharynx in the human papillomavirus era},
  author={Florence K. Keane and Yui‐Hui Chen and Bridget A. Neville and Roy B Tishler and Jonathan D. Schoenfeld and Paul J. Catalano and Danielle N Margalit},
  journal={Cancer},
  year={2015},
  volume={121}
}
Although human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma (OPSCC) tends to present at an advanced nodal stage (N stage), the prognosis is generally better than that for HPV‐negative OPSCC. Prior work has demonstrated the increasing incidence of HPV‐related OPSCC in the United States. This study was designed to determine whether the changing epidemiology of OPSCC is reflected in changes in the prognostic significance of the tumor stage (T stage) and the N stage in a… 

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