Changing patterns of transcriptional and post-transcriptional control of beta-F1-ATPase gene expression during mitochondrial biogenesis in liver.

@article{Izquierdo1995ChangingPO,
  title={Changing patterns of transcriptional and post-transcriptional control of beta-F1-ATPase gene expression during mitochondrial biogenesis in liver.},
  author={J M Izquierdo and Javier Ricart and Luciana L. K. Ostronoff and Gustavo Egea and Jos{\'e} M Cuezva},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 17},
  pages={10342-50}
}
To elucidate the mechanisms that regulate the expression of nuclear genes during biogenesis of mammalian mitochondria, the expression pattern of the beta-subunit of the ATP synthase gene has been characterized in rat liver between day 20 in utero and 12 weeks postnatal. The parallelism existing between transcriptional activity of the gene and the amount of beta-F1-ATPase protein in liver indicates that proliferation of mitochondria is controlled at the transcriptional level. On the other hand… CONTINUE READING
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