Changing numbers of neuronal and non-neuronal cells underlie postnatal brain growth in the rat.

@article{Bandeira2009ChangingNO,
  title={Changing numbers of neuronal and non-neuronal cells underlie postnatal brain growth in the rat.},
  author={Fabiana Bandeira and Roberto Lent and Suzana Herculano-Houzel},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 33},
  pages={14108-13}
}
The rat brain increases >6x in mass from birth to adulthood, presumably through the addition of glial cells and increasing neuronal size, without the addition of neurons. To test this hypothesis, here we investigate quantitatively the postnatal changes in the total number of neuronal and non-neuronal cells in the developing rat brain, and examine how these changes correlate with brain growth. Total numbers of cells were determined with the isotropic fractionator in the brains of 53 Wistar rats… CONTINUE READING
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