Changing motor synergies in chronic stroke.

@article{Dipietro2007ChangingMS,
  title={Changing motor synergies in chronic stroke.},
  author={Laura Dipietro and H. I. Krebs and Susan E. Fasoli and Bruce T. Volpe and Joel Stein and Christopher T. Bever and Neville Hogan},
  journal={Journal of neurophysiology},
  year={2007},
  volume={98 2},
  pages={
          757-68
        }
}
Synergies are thought to be the building blocks of vertebrate movements. The inability to execute synergies in properly timed and graded fashion precludes adequate functional motor performance. In humans with stroke, abnormal synergies are a sign of persistent neurological deficit and result in loss of independent joint control, which disrupts the kinematics of voluntary movements. This study aimed at characterizing training-related changes in synergies apparent from movement kinematics and… 

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References

SHOWING 1-10 OF 123 REFERENCES
Compensatory strategies for reaching in stroke.
TLDR
It is discussed the possibility that there is a critical level of recovery at which patients switch from a strategy employing new degrees of freedom to one in which motor recovery is produced by improving the management of degrees offreedom characteristic of healthy performance.
Deficits in the coordination of multijoint arm movements in patients with hemiparesis: evidence for disturbed control of limb dynamics
TLDR
It is argued that the spatial abnormalities are consistent with an impaired feedforward control of the passive interaction torques which arise during multijoint movements and are hypothesized to reflect a degradation of the internal representation of limb dynamics that occurs either as a primary consequence of brain injury or secondary to disuse.
Quantification of force abnormalities during passive and active-assisted upper-limb reaching movements in post-stroke hemiparesis
TLDR
A method for measuring abnormal upper-limb motor performance in post-stroke hemiparetic subjects, which could complement currently used measurement tools for the evaluation of subjects during recovery from stroke, or during therapeutic interventions.
Combinations of muscle synergies in the construction of a natural motor behavior
TLDR
It is shown that combinations of three time-varying muscle synergies underlie the variety of muscle patterns required to kick in different directions, that the recruitment of these synergies is related to movement kinematics, and that there are similarities among the synergies extracted from different behaviors.
Handedness: dominant arm advantages in control of limb dynamics.
TLDR
The purpose of this study was to further investigate interlimb differences in coordination through analysis of inverse dynamics and electromyography recorded during the performance of reaching movements, and propose that distinct neural control mechanisms are employed for dominant and nondominant arm movements.
Forward and backward axial synergies in man
TLDR
It was found that upper trunk movements are accompanied by movements of hip and knees in the opposite direction, resulting in a slight displacement of the center of gravity projection on the ground.
Evidence for a dynamic-dominance hypothesis of handedness
  • R. Sainburg
  • Biology, Psychology
    Experimental Brain Research
  • 2001
TLDR
The results support the dynamic-dominance hypothesis, indicating that interlimb asymmetries in control arise downstream to visuomotor transformations, when dynamic variables that correspond to the forces required for motion are specified.
Proprioceptive control of multijoint movement: unimanual circle drawing
Abstract The present experiments addressed whether proprioception is used by the central nervous system (CNS) to control the spatial and temporal characteristics of unimanual circle drawing. Circle
Differences in control of limb dynamics during dominant and nondominant arm reaching.
TLDR
Findings strongly suggest that distinct neural control mechanisms are employed for dominant and non dominant arm movements, however, whether interlimb differences in neural strategies are a consequence of asymmetric use of the two arms, or vice versa, is not yet understood.
Motions or muscles? Some behavioral factors underlying robotic assistance of motor recovery.
TLDR
Initial insights about the process of upper-limb behavioral recovery that have emerged from robotic therapy work indicate that movement coordination rather than muscle activation may be the most appropriate focus for robotic therapy.
...
...