Changing incidence of hepatocellular carcinoma in Japan.

  title={Changing incidence of hepatocellular carcinoma in Japan.},
  author={Kunio Okuda and Isaburo Fujimoto and Aya Hanai and Yoshinori Urano},
  journal={Cancer research},
  volume={47 18},
A trend in the incidence of hepatocellular carcinoma (HCC) in Japan was studied from the data of the Osaka Cancer Registry (population, 8,512,351 in 1981) for the period of 1963-1983, the Vital Statistics of Japan, Ministry of Health and Welfare, and the Japan Autopsy Registry which contained 594,132 individually filed cases in the 26-year period from 1958 to 1983. Both cancer registry data and autopsy records showed a more than 2-fold increase in HCC incidence, particularly in the last 10… CONTINUE READING
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