Changing epidemiology of central venous catheter-related bloodstream infections: increasing prevalence of Gram-negative pathogens.

@article{Marcos2011ChangingEO,
  title={Changing epidemiology of central venous catheter-related bloodstream infections: increasing prevalence of Gram-negative pathogens.},
  author={Miguel Marcos and Alex Soriano and Amaia I{\~n}urrieta and Jos{\'e} Antonio Mart{\'i}nez and Alberto Romero and Nazaret Cobos and Cristina Hern{\'a}ndez and Manel Almela and Francesc Marco and Josep Maria Mensa},
  journal={The Journal of antimicrobial chemotherapy},
  year={2011},
  volume={66 9},
  pages={2119-25}
}
OBJECTIVES Gram-positive microorganisms have been the predominant pathogens in central venous catheter-related bloodstream infections (CRBSIs). Recent guidelines recommend empirical therapy according to this and restrict coverage for Gram-negatives to specific circumstances. This study aimed to analyse the epidemiological changes in CRBSIs over the 1991-2008 period and to analyse predictors of Gram-negative CRBSIs. PATIENTS AND METHODS A prospectively collected cohort of patients with… CONTINUE READING
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