Changing colors in mice: an inducible system that delivers.

@article{Mills2001ChangingCI,
  title={Changing colors in mice: an inducible system that delivers.},
  author={Alea A Mills},
  journal={Genes & development},
  year={2001},
  volume={15 12},
  pages={
          1461-7
        }
}
Expression of exogenous genes in mammalian systems can be extremely informative for deciphering the function of an encoded protein or determining the role of a putative regulatory region. In many instances it is desirable or even essential to employ a system that has the ability to be controlled by the experimenter. For example, embryonic lethality that results from expression of an exogenous transgene or disruption of an endogenous gene can be problematic as it precludes examination of the… CONTINUE READING

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