Changing clinical presentation of multiple myeloma.

  title={Changing clinical presentation of multiple myeloma.},
  author={Alberto Riccardi and Paolo G. Gobbi and Gianni Ucci and D Bertoloni and R. Luoni and Lou Rutigliano and Edoardo Ascari},
  journal={European journal of cancer},
  volume={27 11},
We compared the presentation features of three series of patients with multiple myeloma diagnosed between 1960 and 1971 (Kyle R, Mayo Clin Proc, 1975, 50, 29, n = 869), 1972 and 1986 (Clinica Medica, University of Pavia, n = 345) and 1987 and 1990 (Cooperative Group for Study and Treatment of Multiple Myeloma, n = 341). In the most recently diagnosed patients, the percentage of those who had symptoms related to multiple myeloma (i.e. any of bone pain, systemic symptoms, disturbances related to… CONTINUE READING
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